Phenotypes associated with this allele

• Allele Symbol: Cenpu^tm1Hluo
• Allele Name: targeted mutation 1, Hongyu Luo
• Allele ID: MGI:5522669
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cenpu^tm1Hluo/Cenpu^tm1Hluo	involves: 129S1/Sv * 129X1/SvJ * C57BL/6	MGI:5522673

Genotype
MGI:5522673

hm1

• Allelic Composition: Cenpu^tm1Hluo/Cenpu^tm1Hluo
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Small size and hypocellular and disorganized epiblast tissue of Cenpu^tm1Hluo/Cenpu^tm1Hluo embryos

mortality/aging

embryonic lethality between somite formation and embryo turning, complete penetrance ( J:202158 )

• mice die between E7.5 and E9.5

embryo

decreased embryo size ( J:202158 )

• moderately smaller at E6.5

• much smaller at E7.5

abnormal visceral endoderm morphology ( J:202158 )

• somewhat thicker at E6.5

growth/size/body

decreased embryo size ( J:202158 )

• moderately smaller at E6.5

• much smaller at E7.5