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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Zbtb16tm2Geno
targeted mutation 2, Genoway
MGI:5522868
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Zbtb16tm2Geno/Zbtb16tm2Geno Not Specified MGI:5522956


Genotype
MGI:5522956
hm1
Allelic
Composition		 Zbtb16tm2Geno/Zbtb16tm2Geno
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Zbtb16tm2Geno mutation (0 available); any Zbtb16 mutation (30 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
reproductive system phenotype ( J:199097 )
N
• testes exhibit normal spontaneous apoptosis in testicular cells

cellular
abnormal DNA methylation ( J:199097 )
• hypermethylation of CpG dinucleotides in Kit, Crabp2 and Myc genes in the bone marrow and testes compared to in wild-type mice

hematopoietic system
abnormal bone marrow cell physiology ( J:199097 )
• bone marrow cells exhibit increased self-renewal compared with wild-type cells




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory