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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Robo4tm1.1Xby
targeted mutation 1, Xiao-bing Yuan
MGI:5523987
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Robo4tm1.1Xby/Robo4tm1.1Xby involves: C57BL/6 MGI:5523989
cn2
 		Robo4tm1.1Xby/Robo4tm1.1Xby
Emx1tm1(cre)Ito/Emx1+ 		involves: 129P2/OlaHsd * C57BL/6 MGI:5523988


Genotype
MGI:5523989
cn1
Allelic
Composition		 Robo4tm1.1Xby/Robo4tm1.1Xby
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Robo4tm1.1Xby mutation (0 available); any Robo4 mutation (89 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal telencephalon development ( J:202213 )
• transfection of cre recombinase between E14.5-E18.5 results in a severe retardation of the radial migration of transfected neurons




Genotype
MGI:5523988
cn2
Allelic
Composition		 Robo4tm1.1Xby/Robo4tm1.1Xby
Emx1tm1(cre)Ito/Emx1+
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Emx1tm1(cre)Ito mutation (1 available); any Emx1 mutation (34 available)
Robo4tm1.1Xby mutation (0 available); any Robo4 mutation (89 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
nervous system phenotype ( J:202213 )
N
• no gross abnormality in cortical lamination




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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory