Phenotypes associated with this allele

• Allele Symbol: Ddx10^m1J
• Allele Name: mutation 1 Jackson
• Allele ID: MGI:5526028
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ddx10^m1J/Ddx10^m1J	B6;129S1-Ddx10^m1J/GrsrJ	MGI:5693911

Genotype
MGI:5693911

hm1

• Allelic Composition: Ddx10^m1J/Ddx10^m1J
• Genetic Background: B6;129S1-Ddx10^m1J/GrsrJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

skeleton

decreased cranium length ( J:223062 )

decreased bone mineral content ( J:223062 )

♀

decreased areal bone mineral density ( J:223062 )

♀

digestive/alimentary system

cleft palate ( J:223062 )

• occassionally homozygotes have cleft palates and/or maxilla

craniofacial

decreased cranium length ( J:223062 )

cleft palate ( J:223062 )

• occassionally homozygotes have cleft palates and/or maxilla

short snout ( J:223062 )

growth/size/body

cleft palate ( J:223062 )

• occassionally homozygotes have cleft palates and/or maxilla

short snout ( J:223062 )

decreased lean body mass ( J:223062 )

decreased body size ( J:223062 )

• a longitudinal growth study from 4 to 12 weeks of age found decreased body mass curves throughout the assessment

decreased body weight ( J:223062 )

• both female and male homozygotes have lower body weight than heterozygotes from the earliest time point assessed, 4 weeks. with the difference more pronounced in males