All Phenotypes Cd22<tm2Lnit> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Cd22^tm2Lnit
targeted mutation 2, Lars Nitschke
MGI:5526056

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cd22^tm2Lnit/Cd22^tm2Lnit	involves: 129P2/OlaHsd * C57BL/6	MGI:5526061

Allelic Composition	Cd22^tm2Lnit/Cd22^tm2Lnit
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd22^tm2Lnit mutation (0 available); any Cd22 mutation (64 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

immune system phenotype ( J:198790 )

N	• early B cell development in bone marrow is normal

absent mature B cells ( J:198790 )

• lack of mature recirculating B cells in bone marrow

• reduced in number

autoimmune response ( J:198790 )

• increased Calcium ion response to anti-IgM

hematopoietic system

absent mature B cells ( J:198790 )

• lack of mature recirculating B cells in bone marrow

• reduced in number

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24