All Phenotypes Bok<tm1.1Ast> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Bok^tm1.1Ast
targeted mutation 1.1, Andreas Strasser
MGI:5527387

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Bok^tm1.1Ast/Bok^tm1.1Ast	involves: BALB/cJ * C57BL/6	MGI:5527391
cx2	Bok^tm1.1Ast/Bok^tm1.1Ast Tg(IghMyc)22Bri/0	involves: BALB/cJ * C57BL * C57BL/6 * SJL	MGI:5527392

Allelic Composition	Bok^tm1.1Ast/Bok^tm1.1Ast
Genetic Background	involves: BALB/cJ * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bok^tm1.1Ast mutation (0 available); any Bok mutation (22 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

immune system phenotype ( J:203179 )

N	• lymphoid organs have normal hematopoietic cell subset composition • lymphoid and myeloid cells respond normally to apoptotic stimuli

increased thymus weight ( J:203179 )

• minor in female, but not male, mice

increased spleen weight ( J:203179 )

• minor in female, but not male, mice

hematopoietic system

hematopoietic system phenotype ( J:203179 )

N	• lymphoid organs have normal hematopoietic cell subset composition

increased thymus weight ( J:203179 )

• minor in female, but not male, mice

increased spleen weight ( J:203179 )

• minor in female, but not male, mice

endocrine/exocrine glands

increased thymus weight ( J:203179 )

• minor in female, but not male, mice

growth/size/body

increased spleen weight ( J:203179 )

• minor in female, but not male, mice

Allelic Composition	Bok^tm1.1Ast/Bok^tm1.1Ast Tg(IghMyc)22Bri/0
Genetic Background	involves: BALB/cJ * C57BL * C57BL/6 * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bok^tm1.1Ast mutation (0 available); any Bok mutation (22 available)
Tg(IghMyc)22Bri mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

neoplasm

increased lymphoma incidence ( J:203179 )

• as in Tg(IghMyc)22Bri mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/19/2024 MGI 6.24