Phenotypes associated with this allele

• Allele Symbol: Tal1^tm1.1Bgo
• Allele Name: targeted mutation 1.1, Berthold Gottgens
• Allele ID: MGI:5527393
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tal1^tm1.1Bgo/Tal1^tm1.1Bgo	Not Specified	MGI:5527394

Genotype
MGI:5527394

hm1

• Allelic Composition: Tal1^tm1.1Bgo/Tal1^tm1.1Bgo
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hematopoietic system

hematopoietic system phenotype ( J:203178 )

N • hematopoietic stem cells exhibit normal multilineage repopulation capacity

abnormal bone marrow cell morphology/development ( J:203178 )

• small decrease in megakaryocytic erythroid progenitors

• spleen cells produce a 2-fold increase in colony forming unit granulocyte-macrophage

• however, mice exhibit normal numbers of granulocyte-macrophage, common myeloid and common lymphoid progenitors

increased hematopoietic stem cell number ( J:203178 )

• 1.5-fold in short term hematopoietic stem cells