All Phenotypes Col17a1<em7Dcr> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Col17a1^em7Dcr
endonuclease-mediated mutation 7, Derry Roopenian
MGI:5527458

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Col17a1^em7Dcr/Col17a1^em7Dcr	C57BL/6J-Col17a1^em7Dcr/Dcr	MGI:7709257
cx2	Col17a1^em7Dcr/Col17a1^em7Dcr Lamc2^jeb/Lamc2^jeb	B6.Cg-Lamc2^jeb Col17a1^em7Dcr/Dcr	MGI:7709378

Allelic Composition	Col17a1^em7Dcr/Col17a1^em7Dcr
Genetic Background	C57BL/6J-Col17a1^em7Dcr/Dcr

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Col17a1^em7Dcr mutation (0 available); any Col17a1 mutation (51 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

integument

abnormal skin tensile strength ( J:352187 )

• slightly improved average skin tensile strength relative to C57BL/6J

Allelic Composition	Col17a1^em7Dcr/Col17a1^em7Dcr Lamc2^jeb/Lamc2^jeb
Genetic Background	B6.Cg-Lamc2^jeb Col17a1^em7Dcr/Dcr

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Col17a1^em7Dcr mutation (0 available); any Col17a1 mutation (51 available)
Lamc2^jeb mutation (4 available); any Lamc2 mutation (70 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

integument

decreased skin tensile strength ( J:352187 )

• The small in-frame deletion in Col17a1 does not alter the junctional epidermolysis bullosa phenotype as assessed in the tail or ear skin or in skin tension

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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