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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Col17a1em14Dcr
endonuclease-mediated mutation 14, Derry Roopenian
MGI:5527468
Summary 2 genotypes


Genotype
MGI:7709340
hm1
Allelic
Composition		 Col17a1em14Dcr/Col17a1em14Dcr
Genetic
Background		 C57BL/6J-Col17a1em14Dcr/Dcr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Col17a1em14Dcr mutation (0 available); any Col17a1 mutation (51 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
integument
integument phenotype ( J:352187 )
N
• No abnormalities were detected up to 37 weeks of age




Genotype
MGI:7709349
cx2
Allelic
Composition		 Col17a1em14Dcr/Col17a1em14Dcr
Lamc2jeb/Lamc2jeb
Genetic
Background		 B6.Cg-Lamc2jeb Col17a1em14Dcr/Dcr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Col17a1em14Dcr mutation (0 available); any Col17a1 mutation (51 available)
Lamc2jeb mutation (4 available); any Lamc2 mutation (70 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
integument
decreased skin tensile strength ( J:352187 )
• At 10 weeks of age compared with the protective PWK/PhJ allele there is no significant difference in tail skin tensile strength but by 20 days of age the strength is found to be less than that of PWK/PhJ but more than with the pure C57BL/6J allele. The ear sores are delayed in onset relative to those on a wild type C57BL/6J background but not to the degree that the PWK/PhJ allele of Col17a1 confers.




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory