cellular
• mouse embryonic fibroblasts fail to form functional flotilin
• however, caveolar membrane microdomains form
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Allele Symbol Allele Name Allele ID |
Flot2tm1Mak targeted mutation 1, Tak Mak MGI:5527543 |
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Summary |
2 genotypes
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
• mouse embryonic fibroblasts fail to form functional flotilin
• however, caveolar membrane microdomains form
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
• as in Tg(MMTV-PyVT)634Mul mice
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• as in Tg(MMTV-PyVT)634Mul mice
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• 10-fold fewer visible macro-metastases in the lungs compared to in Tg(MMTV-PyVT)634Mul mice
• fewer micro-metastases in the lungs compared to in Tg(MMTV-PyVT)634Mul mice
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• as in Tg(MMTV-PyVT)634Mul mice
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• as in Tg(MMTV-PyVT)634Mul mice
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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