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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gt(ROSA)26Sortm1(DTA)Kio
targeted mutation 1, Dimitris Kioussis
MGI:5528898
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Gt(ROSA)26Sortm1(DTA)Kio/Gt(ROSA)26Sor+
Tg(Tnfrsf4-cre)1Nik/0 		B6.129-Tnfrsf4tm2(cre)Nik Gt(ROSA)26Sortm1(DTA)Kio MGI:5529105


Genotype
MGI:5529105
cn1
Allelic
Composition		 Gt(ROSA)26Sortm1(DTA)Kio/Gt(ROSA)26Sor+
Tg(Tnfrsf4-cre)1Nik/0
Genetic
Background		 B6.129-Tnfrsf4tm2(cre)Nik Gt(ROSA)26Sortm1(DTA)Kio
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1(DTA)Kio mutation (0 available); any Gt(ROSA)26Sor mutation (993 available)
Tg(Tnfrsf4-cre)1Nik mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
growth/size/body
decreased body size ( J:203905 )
• in a small proportion of mice as early as weaning
postnatal growth retardation ( J:203905 )
• in a small proportion of mice as early as weaning

endocrine/exocrine glands
exocrine pancreas atrophy ( J:203905 )
• without inflammatory infiltrates in a small proportion of mice

digestive/alimentary system
exocrine pancreas atrophy ( J:203905 )
• without inflammatory infiltrates in a small proportion of mice




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory