Phenotypes associated with this allele

• Allele Symbol: Gfy^tm1Yyos
• Allele Name: targeted mutation 1, Yoshihiro Yoshihara
• Allele ID: MGI:5529101
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Gfy^tm1Yyos/Gfy^tm1Yyos	B6.129S-Gfy^tm1Yyos	MGI:5529102

Genotype
MGI:5529102

hm1

• Allelic Composition: Gfy^tm1Yyos/Gfy^tm1Yyos
• Genetic Background: B6.129S-Gfy^tm1Yyos

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

taste/olfaction

abnormal olfactory epithelium morphology ( J:199864 )

• abnormal localization of ADCY3 suggesting impaired intracellular trafficking

abnormal olfactory epithelium cilium morphology ( J:199864 )

• short

abnormal olfactory epithelium physiology ( J:199864 )

• local field potentials in response to various odorants are reduced

impaired olfaction ( J:199864 )

• decrease in sensitivity to TMT ((a component of fox feces odor) in a fear response assay at low and moderate concentrations

• however, response at the highest concentration is similar to controls

craniofacial

abnormal olfactory epithelium morphology ( J:199864 )

• abnormal localization of ADCY3 suggesting impaired intracellular trafficking

abnormal olfactory epithelium cilium morphology ( J:199864 )

• short

respiratory system

abnormal olfactory epithelium morphology ( J:199864 )

• abnormal localization of ADCY3 suggesting impaired intracellular trafficking

abnormal olfactory epithelium cilium morphology ( J:199864 )

• short

abnormal olfactory epithelium physiology ( J:199864 )

• local field potentials in response to various odorants are reduced

cellular

abnormal olfactory epithelium cilium morphology ( J:199864 )

• short

growth/size/body

abnormal olfactory epithelium morphology ( J:199864 )

• abnormal localization of ADCY3 suggesting impaired intracellular trafficking

abnormal olfactory epithelium cilium morphology ( J:199864 )

• short