Analysis Tools
immune system
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• following C. albicans challenge, peritoneal macrophage exhibit reduced release of arachidonic acid and fail to produce TNF compared with wild-type cells
• however, macrophage exhibit normal arachidonic acid release in response to PMA and lipid metabolism
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• of non-opsonized C. albicans
• no improvement with IL13 treatment
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• in response to heat-killed C. albicans or non-opsonized zymosan
• however, response to LPS is normal
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• following C. albicans challenge, macrophage exhibit reduced release of arachidonic acid, C. albicans phagocytosis, reactive oxygen species production (whether treated with IL13 and/or mannan or not) and yeast clearance compared with control cells
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hematopoietic system
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• following C. albicans challenge, peritoneal macrophage exhibit reduced release of arachidonic acid and fail to produce TNF compared with wild-type cells
• however, macrophage exhibit normal arachidonic acid release in response to PMA and lipid metabolism
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• of non-opsonized C. albicans
• no improvement with IL13 treatment
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cellular
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• of non-opsonized C. albicans
• no improvement with IL13 treatment
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