Phenotypes associated with this allele

• Allele Symbol: Vsig4^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5529618
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Vsig4^tm1b(EUCOMM)Hmgu/Vsig4^tm1b(EUCOMM)Hmgu	C57BL/6N-Vsig4^tm1b(EUCOMM)Hmgu/J	MGI:5797909
ot2	Vsig4^tm1b(EUCOMM)Hmgu/Y	C57BL/6N-Vsig4^tm1b(EUCOMM)Hmgu/J	MGI:6480629

Genotype
MGI:5797909

hm1

• Allelic Composition: Vsig4^{tm1b(EUCOMM)Hmgu}/Vsig4^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Vsig4^{tm1b(EUCOMM)Hmgu}/J
• Cell Lines: HEPD0753_3_G03

Data Sources

IMPC Data for Vsig4

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

decreased total body fat amount ( J:211773 )

♀

IMPC - JAX

behavior/neurological

hyperactivity ( J:211773 )

♀

IMPC - JAX

increased vertical activity ( J:211773 )

♀

IMPC - JAX

abnormal sleep behavior ( J:211773 )

♀

IMPC - JAX

cardiovascular system

increased heart weight ( J:211773 )

♀

IMPC - JAX

growth/size/body

increased heart weight ( J:211773 )

♀

IMPC - JAX

increased lean body mass ( J:211773 )

♀

IMPC - JAX

homeostasis/metabolism

increased blood urea nitrogen level ( J:211773 )

♀

IMPC - JAX

decreased circulating glucose level ( J:211773 )

♀

IMPC - JAX

increased circulating sodium level ( J:211773 )

♀

IMPC - JAX

increased urine microalbumin level ( J:211773 )

♀

IMPC - JAX

renal/urinary system

increased urine microalbumin level ( J:211773 )

♀

IMPC - JAX

Genotype
MGI:6480629

ot2

• Allelic Composition: Vsig4^{tm1b(EUCOMM)Hmgu}/Y
• Genetic Background: C57BL/6N-Vsig4^{tm1b(EUCOMM)Hmgu}/J
• Cell Lines: HEPD0753_3_G03

Data Sources

IMPC Data for Vsig4

adipose tissue

decreased total body fat amount ( J:211773 )

♂

IMPC - JAX

behavior/neurological

decreased locomotor activity ( J:211773 )

♂

IMPC - JAX

growth/size/body

increased lean body mass ( J:211773 )

♂

IMPC - JAX

hematopoietic system

decreased mean corpuscular hemoglobin ( J:211773 )

♂

IMPC - JAX

homeostasis/metabolism

decreased circulating glucose level ( J:211773 )

♂

IMPC - JAX

increased circulating potassium level ( J:211773 )

♂

IMPC - JAX

increased circulating alanine transaminase level ( J:211773 )

♂

IMPC - JAX

increased circulating alkaline phosphatase level ( J:211773 )

♂

IMPC - JAX

increased circulating aspartate transaminase level ( J:211773 )

♂

IMPC - JAX

abnormal cholesterol homeostasis ( J:211773 )

♂

IMPC - JAX

increased urine microalbumin level ( J:211773 )

♂

IMPC - JAX

renal/urinary system

increased urine microalbumin level ( J:211773 )

♂

IMPC - JAX