Phenotypes associated with this allele

• Allele Symbol: Aurka^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5529637
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Aurka^tm1b(EUCOMM)Hmgu/Aurka^tm1b(EUCOMM)Hmgu	B6N(Cg)-Aurka^tm1b(EUCOMM)Hmgu/J	MGI:5767576
ht2	Aurka^tm1b(EUCOMM)Hmgu/Aurka^+	B6N(Cg)-Aurka^tm1b(EUCOMM)Hmgu/J	MGI:5797391

Genotype
MGI:5767576

hm1

• Allelic Composition: Aurka^{tm1b(EUCOMM)Hmgu}/Aurka^{tm1b(EUCOMM)Hmgu}
• Genetic Background: B6N(Cg)-Aurka^{tm1b(EUCOMM)Hmgu}/J
• Cell Lines: HEPD0510_4_F05

Data Sources

IMPC Data for Aurka

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - JAX

embryonic lethality prior to organogenesis ( J:211773 )

IMPC - JAX

preweaning lethality, complete penetrance ( J:211773 )

IMPC - JAX

Genotype
MGI:5797391

ht2

• Allelic Composition: Aurka^{tm1b(EUCOMM)Hmgu}/Aurka⁺
• Genetic Background: B6N(Cg)-Aurka^{tm1b(EUCOMM)Hmgu}/J
• Cell Lines: HEPD0510_4_F05

Data Sources

IMPC Data for Aurka

hematopoietic system

decreased leukocyte cell number ( J:211773 )

IMPC - JAX

immune system

decreased leukocyte cell number ( J:211773 )

IMPC - JAX

skeleton

abnormal bone structure ( J:211773 )

♀

IMPC - JAX

vision/eye

sclerocornea ( J:211773 )

♀

IMPC - JAX