homeostasis/metabolism
• inhibited autophagy in the lens at E16
|
vision/eye
• inhibited autophagy in the lens at E16
• impaired differentiation of secondary lens fiber cells with accumulation of vacuoles
• however, organelle degradation is normal
|
small lens
(
J:198392
)
• at P0.5, P7.5 and 2 months
|
• at birth and more pronounced at 2 months
|
cellular
• inhibited autophagy in the lens at E16
|