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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Rapgef3tm1Skc
targeted mutation 1, Sookja K Chung
MGI:5532318
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Rapgef3tm1Skc/Rapgef3tm1Skc Not Specified MGI:5532322


Genotype
MGI:5532322
hm1
Allelic
Composition
Rapgef3tm1Skc/Rapgef3tm1Skc
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rapgef3tm1Skc mutation (0 available); any Rapgef3 mutation (47 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• in stimulated insulin secreting cells derived from ES cells
• in glucose-injected mice
• in mice fed a high-fat diet
• early onset after multiple-low-dose streptozotocin administration
• after glucose injection
• without an increase in oxygen consumption or locomotor activity
• mild in mice fed standard chow
• in mice fed a high-fat diet
• in mice fed a high-fat diet

endocrine/exocrine glands
• in mice fed a high-fat diet
• in mice fed a high-fat diet
• increased apoptosis after multiple-low-dose streptozotocin administration
• in glucose-injected mice
• in stimulated insulin secreting cells derived from ES cells
• severe after multiple-low-dose streptozotocin administration

growth/size/body
• at 36 weeks
• in mice fed a high-fat diet

immune system
• severe after multiple-low-dose streptozotocin administration





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory