About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ubr4tm1.1Nkt
targeted mutation 1.1, Yoshihiro Nakatani
MGI:5532331
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ubr4tm1.1Nkt/Ubr4tm1.1Nkt involves: 129S6/SvEvTac * C57BL/6 * FVB/N MGI:5532400


Genotype
MGI:5532400
hm1
Allelic
Composition		 Ubr4tm1.1Nkt/Ubr4tm1.1Nkt
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ubr4tm1.1Nkt mutation (0 available); any Ubr4 mutation (247 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

Growth retardation in E9.5-E12.5 Ubr4tm1.1Nkt/Ubr4tm1.1Nkt embryos

mortality/aging
embryonic lethality during organogenesis, complete penetrance ( J:203460 )
• fewer than expected mice are present after E11.5 with no mice detected at E13.5

embryo
abnormal placental labyrinth vasculature morphology ( J:203460 )
• dilated and disorganized maternal blood vessels full of serum and with monocytes marginated along the endothelial inner lining
decreased embryo size ( J:203460 )
• beginning at E10.5

cardiovascular system
abnormal placental labyrinth vasculature morphology ( J:203460 )
• dilated and disorganized maternal blood vessels full of serum and with monocytes marginated along the endothelial inner lining

growth/size/body
decreased embryo size ( J:203460 )
• beginning at E10.5




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory