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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Ubr4tm1.1Nkt
targeted mutation 1.1, Yoshihiro Nakatani
MGI:5532331
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Ubr4tm1.1Nkt/Ubr4tm1.1Nkt involves: 129S6/SvEvTac * C57BL/6 * FVB/N MGI:5532400


Genotype
MGI:5532400
hm1
Allelic
Composition
Ubr4tm1.1Nkt/Ubr4tm1.1Nkt
Genetic
Background
involves: 129S6/SvEvTac * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ubr4tm1.1Nkt mutation (0 available); any Ubr4 mutation (247 available)
phenotype observed in females
phenotype observed in males
N normal phenotype

Growth retardation in E9.5-E12.5 Ubr4tm1.1Nkt/Ubr4tm1.1Nkt embryos

mortality/aging
• fewer than expected mice are present after E11.5 with no mice detected at E13.5

embryo
• dilated and disorganized maternal blood vessels full of serum and with monocytes marginated along the endothelial inner lining
• beginning at E10.5

cardiovascular system
• dilated and disorganized maternal blood vessels full of serum and with monocytes marginated along the endothelial inner lining

growth/size/body
• beginning at E10.5





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory