Phenotypes associated with this allele

• Allele Symbol: Nr6a1^{tm1d(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1d, Wellcome Trust Sanger Institute
• Allele ID: MGI:5532717
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Nr6a1^tm1d(EUCOMM)Wtsi/Nr6a1^tm1d(EUCOMM)Wtsi	involves: 129S/SvEv * C57BL/6 * C57BL/6N * SJL	MGI:5532735

Genotype
MGI:5532735

hm1

• Allelic Composition: Nr6a1^{tm1d(EUCOMM)Wtsi}/Nr6a1^{tm1d(EUCOMM)Wtsi}
• Genetic Background: involves: 129S/SvEv * C57BL/6 * C57BL/6N * SJL
• Cell Lines: EPD0105_6_D03

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Morphological defects in E9.5 Nr6a1^{tm1d(EUCOMM)Wtsi}/Nr6a1^{tm1d(EUCOMM)Wtsi} embryos

mortality/aging

embryonic lethality, complete penetrance ( J:204241 )

• authors state that mice exhibit severe morphological defects similar to those in Nr6a1^tm1Coo homozygotes

embryo

abnormal embryo development ( J:204241 )

• authors state that mice exhibit severe morphological defects similar to those in Nr6a1^tm1Coo homozygotes

incomplete embryo turning ( J:204241 )

• embryos fail to turn from the lordotic to the fetal position

decreased embryo size ( J:204241 )

• at E9.5

impaired somite development ( J:204241 )

• truncated somitogenesis

growth/size/body

decreased embryo size ( J:204241 )

• at E9.5