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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ank3tm2.1Bnt
targeted mutation 2.1, Vann Bennett
MGI:5538265
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Ank3tm2.1Bnt/Ank3tm2.1Bnt
Tg(Nes-cre)1Kln/? 		involves: 129X1/SvJ * C57BL/6 * SJL/J MGI:5829760


Genotype
MGI:5829760
cn1
Allelic
Composition		 Ank3tm2.1Bnt/Ank3tm2.1Bnt
Tg(Nes-cre)1Kln/?
Genetic
Background		 involves: 129X1/SvJ * C57BL/6 * SJL/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ank3tm2.1Bnt mutation (1 available); any Ank3 mutation (170 available)
Tg(Nes-cre)1Kln mutation (4 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
perinatal lethality ( J:218905 )
• mice die immediately after birth

nervous system
abnormal axon morphology ( J:218905 )
• proximal axon develops dendritic properties such as dendritic spines, however, in hippocampal cultures axon characteristics resume 50-100 um from the soma




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory