Phenotypes associated with this allele

• Allele Symbol: Ank3^tm2.2Bnt
• Allele Name: targeted mutation 2.2, Vann Bennett
• Allele ID: MGI:5538266
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ank3^tm2.2Bnt/Ank3^tm2.2Bnt	involves: 129S4/SvJaeSor * 129X1/SvJ * C57BL/6 * FVB/N	MGI:5538268

Genotype
MGI:5538268

hm1

• Allelic Composition: Ank3^tm2.2Bnt/Ank3^tm2.2Bnt
• Genetic Background: involves: 129S4/SvJaeSor * 129X1/SvJ * C57BL/6 * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

postnatal lethality, complete penetrance ( J:198370 )

• Background Sensitivity: mice on a mixed 129 and C57BL/6 background do not survive beyond P2

prenatal lethality, incomplete penetrance ( J:198370 )

• Background Sensitivity: most mice die before birth on a more pure C57BL/6 background compared with mice on a mixed 129 and C57BL/6 backgrounds that survive to birth

renal/urinary system

abnormal kidney collecting duct epithelium morphology ( J:198370 )

• reduced lateral membrane height

respiratory system

abnormal bronchus epithelium morphology ( J:198370 )

• reduced lateral membrane height