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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Lhcgrtm1.1Pnara
targeted mutation 1.1, Prema Narayan
MGI:5538310
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
ht1
Lhcgrtm1.1Pnara/Lhcgr+ involves: 129S1/SvImJ * 129X1/SvJ * C57BL/6J MGI:5538381


Genotype
MGI:5538381
ht1
Allelic
Composition
Lhcgrtm1.1Pnara/Lhcgr+
Genetic
Background
involves: 129S1/SvImJ * 129X1/SvJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lhcgrtm1.1Pnara mutation (1 available); any Lhcgr mutation (43 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
N
• mice exhibit normal Sertoli cell development and sperm
• precocious development of adult Leydig cells
• as early as 7 days, persisting through adulthood
• P10 to 3 weeks
• in male mice

homeostasis/metabolism
• increased in testes from P7
• at 15 days in male mice indicating precocious puberty

renal/urinary system
• at 15 days in male mice indicating precocious puberty

endocrine/exocrine glands
• precocious development of adult Leydig cells
• as early as 7 days, persisting through adulthood





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory