Phenotypes associated with this allele

• Allele Symbol: Oxtr^tm1Knis
• Allele Name: targeted mutation 1, Katsuhiko Nishimori
• Allele ID: MGI:5543243
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Oxtr^tm1Knis/Oxtr^tm1Knis	B6N.129P2-Oxtr^tm1Knis	MGI:5543252

Genotype
MGI:5543252

cn1

• Allelic Composition: Oxtr^tm1Knis/Oxtr^tm1Knis
• Genetic Background: B6N.129P2-Oxtr^tm1Knis

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

behavior/neurological phenotype ( J:203893 )

N • following social defeat, mice exhibit normal tone-dependent fear conditioning

abnormal learning/memory/conditioning ( J:203893 )

• following social defeat, mice injected with a cre-expressing adenovirus into the lateral septum fail to exhibit a decreased in social interaction unlike control mice

abnormal contextual conditioning behavior ( J:203893 )

• following social defeat, mice injected with a cre-expressing adenovirus into the lateral septum exhibit the same amount of freezing as unstressed mice unlike in control mice

abnormal social investigation ( J:203893 )

• following social defeat, mice injected with a cre-expressing adenovirus into the lateral septum fail to exhibit a decreased in social interaction unlike control mice

• however, mice exhibit normal response to social defeat