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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Utf1tm1Okud
targeted mutation 1, Akihiko Okuda
MGI:5543270
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Utf1tm1Okud/Utf1tm1Okud B6.129P2-Utf1tm1Okud MGI:5543291
hm2
Utf1tm1Okud/Utf1tm1Okud involves: 129P2/OlaHsd * C57BL/6J * ICR MGI:5543292


Genotype
MGI:5543291
hm1
Allelic
Composition
Utf1tm1Okud/Utf1tm1Okud
Genetic
Background
B6.129P2-Utf1tm1Okud
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Utf1tm1Okud mutation (1 available); any Utf1 mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype

Growth retardation in Utf1tm1Okud/Utf1tm1Okud mutants

mortality/aging
• Background Sensitivity: mice on a C57BL/6J congenic background do not survive more than 2 days after birth unlike mice on a mixed background that are viable
• Background Sensitivity: most mice on a C57BL/6J congenic background die within a day after birth unlike mice on a mixed background that are viable

embryo
• at E14.5 due to delayed development
• at E14.5 due to delayed development
• delayed with reduced mitotic activity

growth/size/body
• evident mid-gestation (E14.5 and E16.5)

cardiovascular system
• at E14.5 due to delayed development

skeleton
• delay in the replacement of cartilaginous ribs with ossified ribs at E16.5

cellular
• in the placenta

muscle
• at E14.5 due to delayed development




Genotype
MGI:5543292
hm2
Allelic
Composition
Utf1tm1Okud/Utf1tm1Okud
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6J * ICR
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Utf1tm1Okud mutation (1 available); any Utf1 mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
N
• Background Sensitivity: mice on a mixed background are viable unlike mice on a C57BL/6J congenic background that soon after birth

reproductive system
N
• mice are fertile

growth/size/body
• at 4 weeks





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory