All Phenotypes Cd44<tm1Stpa> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Cd44^tm1Stpa
targeted mutation 1, Steven T Pals
MGI:5544103

Summary

3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cd44^tm1Stpa/Cd44^tm1Stpa	B6.Cg-Cd44^tm1Stpa	MGI:5544110
cx2	Apc^Min/Apc⁺ Cd44^tm1Stpa/Cd44^tm2Stpa	involves: C57BL/6J	MGI:5544114
cx3	Apc^Min/Apc⁺ Cd44^tm1Stpa/Cd44^tm1Stpa	involves: C57BL/6J * C57BL/6JIco	MGI:5544111

Allelic Composition	Cd44^tm1Stpa/Cd44^tm1Stpa
Genetic Background	B6.Cg-Cd44^tm1Stpa

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd44^tm1Stpa mutation (0 available); any Cd44 mutation (72 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

digestive/alimentary system

digestive/alimentary phenotype ( J:204874 )

N	• mice exhibit normal intestinal crypts

Allelic Composition	Apc^Min/Apc⁺ Cd44^tm1Stpa/Cd44^tm2Stpa
Genetic Background	involves: C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apc^Min mutation (12 available); any Apc mutation (158 available)
Cd44^tm1Stpa mutation (0 available); any Cd44 mutation (72 available)
Cd44^tm2Stpa mutation (0 available); any Cd44 mutation (72 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

neoplasm

increased intestinal adenoma incidence ( J:204874 )

• mice develop the same number of intestinal adenoma and microadenoma as in Apc^Min heterozygotes

digestive/alimentary system

increased intestinal adenoma incidence ( J:204874 )

• mice develop the same number of intestinal adenoma and microadenoma as in Apc^Min heterozygotes

Allelic Composition	Apc^Min/Apc⁺ Cd44^tm1Stpa/Cd44^tm1Stpa
Genetic Background	involves: C57BL/6J * C57BL/6JIco

Find Mice

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

premature death ( J:204874 )

• as in Apc^Min heterozygotes

neoplasm

increased intestinal adenoma incidence ( J:204874 )

• mice develop the same number of intestinal adenoma and microadenoma as in Apc^Min heterozygotes

digestive/alimentary system

increased intestinal adenoma incidence ( J:204874 )

• mice develop the same number of intestinal adenoma and microadenoma as in Apc^Min heterozygotes

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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