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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Svoptm1.1Baj
targeted mutation 1.1, Sandra M Bajjalieh
MGI:5544573
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Svoptm1.1Baj/Svoptm1.1Baj involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6Ncr MGI:5544579
cx2
 		Sv2atm1Baj/Sv2atm1Baj
Sv2btm1Baj/Sv2btm1Baj
Svoptm1.1Baj/Svoptm1.1Baj 		involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6Ncr MGI:5544580


Genotype
MGI:5544579
hm1
Allelic
Composition		 Svoptm1.1Baj/Svoptm1.1Baj
Genetic
Background		 involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6Ncr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Svoptm1.1Baj mutation (0 available); any Svop mutation (32 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:204383 )
• mice are viable and phenotypically normal (including normal synaptic vesicle protein content, motor coordination and circadian behavior)




Genotype
MGI:5544580
cx2
Allelic
Composition		 Sv2atm1Baj/Sv2atm1Baj
Sv2btm1Baj/Sv2btm1Baj
Svoptm1.1Baj/Svoptm1.1Baj
Genetic
Background		 involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6Ncr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sv2atm1Baj mutation (2 available); any Sv2a mutation (37 available)
Sv2btm1Baj mutation (2 available); any Sv2b mutation (58 available)
Svoptm1.1Baj mutation (0 available); any Svop mutation (32 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
postnatal lethality, complete penetrance ( J:204383 )
• mice die within 3 weeks of birth as in Sv2atm1Baj Sv2btm1Baj double homozygotes

growth/size/body
postnatal growth retardation ( J:204383 )
• mice fail to grow as in Sv2atm1Baj Sv2btm1Baj double homozygotes




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory