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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gdf11tm1.1Vlcg
targeted mutation 1.1, Velocigene
MGI:5544775
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Gdf11tm1.1Vlcg/Gdf11tm1.1Vlcg involves: 129S6/SvEvTac * C57BL/6NTac MGI:5546221
cn2
 		Gdf11tm1.1Vlcg/Gdf11tm1.1Vlcg
Tg(Nanog-cre)#Vlcg/0 		involves: 129S6/SvEvTac * C57BL/6NTac MGI:5546222


Genotype
MGI:5546221
hm1
Allelic
Composition		 Gdf11tm1.1Vlcg/Gdf11tm1.1Vlcg
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gdf11tm1.1Vlcg mutation (0 available); any Gdf11 mutation (13 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
limbs/digits/tail
limbs/digits/tail phenotype ( J:200671 )
N
• normal tail length

skeleton
increased rib number ( J:200671 )
• an extra rib occasionally (6 of 19 mice with an extra thoracic rib)




Genotype
MGI:5546222
cn2
Allelic
Composition		 Gdf11tm1.1Vlcg/Gdf11tm1.1Vlcg
Tg(Nanog-cre)#Vlcg/0
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gdf11tm1.1Vlcg mutation (0 available); any Gdf11 mutation (13 available)
Tg(Nanog-cre)#Vlcg mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
craniofacial
cleft palate ( J:200671 )
• authors state that mice phenocopy Gdf11tm1Sjl homozygotes

limbs/digits/tail
short tail ( J:200671 )
• authors state that mice phenocopy Gdf11tm1Sjl homozygotes

digestive/alimentary system
cleft palate ( J:200671 )
• authors state that mice phenocopy Gdf11tm1Sjl homozygotes

growth/size/body
cleft palate ( J:200671 )
• authors state that mice phenocopy Gdf11tm1Sjl homozygotes




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory