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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Droshatm3Vlcg
targeted mutation 3, Velocigene
MGI:5546234
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Droshatm3Vlcg/Droshatm3Vlcg involves: 129S6/SvEvTac * C57BL/6NTac MGI:5546237
cn2
 		Droshatm2.1Vlcg/Droshatm3Vlcg
Tg(Nanog-cre)#Vlcg/0 		involves: 129S6/SvEvTac * C57BL/6NTac MGI:5546235
cn3
 		Droshatm1.1Vlcg/Droshatm3Vlcg
Gt(ROSA)26Sortm3.1(cre/ERT2)Vlcg/Gt(ROSA)26Sor+ 		involves: 129S6/SvEvTac * C57BL/6NTac MGI:5546236


Genotype
MGI:5546237
hm1
Allelic
Composition		 Droshatm3Vlcg/Droshatm3Vlcg
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Droshatm3Vlcg mutation (0 available); any Drosha mutation (96 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging




Genotype
MGI:5546235
cn2
Allelic
Composition		 Droshatm2.1Vlcg/Droshatm3Vlcg
Tg(Nanog-cre)#Vlcg/0
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Droshatm2.1Vlcg mutation (0 available); any Drosha mutation (96 available)
Droshatm3Vlcg mutation (0 available); any Drosha mutation (96 available)
Tg(Nanog-cre)#Vlcg mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging




Genotype
MGI:5546236
cn3
Allelic
Composition		 Droshatm1.1Vlcg/Droshatm3Vlcg
Gt(ROSA)26Sortm3.1(cre/ERT2)Vlcg/Gt(ROSA)26Sor+
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Droshatm1.1Vlcg mutation (0 available); any Drosha mutation (96 available)
Droshatm3Vlcg mutation (0 available); any Drosha mutation (96 available)
Gt(ROSA)26Sortm3.1(cre/ERT2)Vlcg mutation (0 available); any Gt(ROSA)26Sor mutation (993 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
mortality/aging ( J:200671 )
N
• tamoxifen-treated mice are born and survive

growth/size/body
decreased body size ( J:200671 )
• tamoxifen-treated mice are runted




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory