About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tnfrsf21tm1Arte
targeted mutation 1, TaconicArtemis
MGI:5546637
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Tnfrsf21tm1Arte/Tnfrsf21tm1Arte involves: C57BL/6NTac MGI:5547355


Genotype
MGI:5547355
hm1
Allelic
Composition		 Tnfrsf21tm1Arte/Tnfrsf21tm1Arte
Genetic
Background		 involves: C57BL/6NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tnfrsf21tm1Arte mutation (0 available); any Tnfrsf21 mutation (61 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal oligodendrocyte apoptosis ( J:205651 )
• reduced number of apoptotic oligodendrocytes from cultured oligodendrocyte progenitor cells in differentiation medium compared with cultured wild-type cells
increased oligodendrocyte number ( J:205651 )
• 2.5-fold more oligodendrocytes with fewer apoptotic oligodendrocytes from cultured oligodendrocyte progenitor cells in differentiation medium compared with cultured wild-type cells
abnormal myelination ( J:205651 )
• early-onset myelination during development

cellular
abnormal oligodendrocyte apoptosis ( J:205651 )
• reduced number of apoptotic oligodendrocytes from cultured oligodendrocyte progenitor cells in differentiation medium compared with cultured wild-type cells




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory