About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Irak2tm1.1Pcoh
targeted mutation 1.1, Philip Cohen
MGI:5548123
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Irak1tm1.1Pcoh/?
Irak2tm1.1Pcoh/? 		involves: 129P2/OlaHsd * C57BL/6 MGI:5548134
ot2
 		Irak2tm1.1Pcoh/? involves: C57BL/6 MGI:5548131


Genotype
MGI:5548134
cx1
Allelic
Composition		 Irak1tm1.1Pcoh/?
Irak2tm1.1Pcoh/?
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Irak1tm1.1Pcoh mutation (0 available); any Irak1 mutation (16 available)
Irak2tm1.1Pcoh mutation (0 available); any Irak2 mutation (58 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased interferon-alpha secretion ( J:205798 )
• from plasmacytoid dendritic cell stimulated with CpG-B, CpG-A or the TLR7 agonist poly(dU)




Genotype
MGI:5548131
ot2
Allelic
Composition		 Irak2tm1.1Pcoh/?
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Irak2tm1.1Pcoh mutation (0 available); any Irak2 mutation (58 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased interferon-alpha secretion ( J:205798 )
• from plasmacytoid dendritic cell stimulated with CpG-B, CpG-A or the TLR7 agonist poly(dU)




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory