Phenotypes associated with this allele

• Allele Symbol: Thpo^{tm1.1(KOMP)Vlcg}
• Allele Name: targeted mutation 1.1, Velocigene
• Allele ID: MGI:5548323
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Thpo^tm1.1(KOMP)Vlcg/Thpo^tm1.1(KOMP)Vlcg	C57BL/6N-Thpo^tm1.1(KOMP)Vlcg/MbpMmucd	MGI:6461740
hm2	Thpo^tm1.1(KOMP)Vlcg/Thpo^tm1.1(KOMP)Vlcg	C57BL/6N-Thpo^tm1.1(KOMP)Vlcg/Ucd	MGI:5797864

Genotype
MGI:6461740

hm1

• Allelic Composition: Thpo^{tm1.1(KOMP)Vlcg}/Thpo^{tm1.1(KOMP)Vlcg}
• Genetic Background: C57BL/6N-Thpo^{tm1.1(KOMP)Vlcg}/MbpMmucd
• Cell Lines: 12573A-H6

Data Sources

IMPC Data for Thpo

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

decreased bronchoconstrictive response ( J:211773 )

♂

IMPC - TCP

respiratory system

decreased bronchoconstrictive response ( J:211773 )

♂

IMPC - TCP

increased pulmonary respiratory rate ( J:211773 )

IMPC - TCP

decreased pulmonary ventilation ( J:211773 )

IMPC - TCP

Genotype
MGI:5797864

hm2

• Allelic Composition: Thpo^{tm1.1(KOMP)Vlcg}/Thpo^{tm1.1(KOMP)Vlcg}
• Genetic Background: C57BL/6N-Thpo^{tm1.1(KOMP)Vlcg}/Ucd
• Cell Lines: 12573A-H6

Data Sources

IMPC Data for Thpo

craniofacial

abnormal cranium morphology ( J:211773 )

♀

IMPC - UCD

hematopoietic system

thrombocytopenia ( J:211773 )

IMPC - UCD

increased mean platelet volume ( J:211773 )

♀

IMPC - UCD

skeleton

abnormal cranium morphology ( J:211773 )

♀

IMPC - UCD

vision/eye

cornea opacity ( J:211773 )

♂

IMPC - UCD