Phenotypes associated with this allele

• Allele Symbol: Tead1^{tm1b(KOMP)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5548324
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tead1^tm1b(KOMP)Wtsi/Tead1^tm1b(KOMP)Wtsi	C57BL/6N-Tead1^tm1b(KOMP)Wtsi/Bay	MGI:5757797
ht2	Tead1^tm1b(KOMP)Wtsi/Tead1^+	C57BL/6N-Tead1^tm1b(KOMP)Wtsi/Bay	MGI:5757796

Genotype
MGI:5757797

hm1

• Allelic Composition: Tead1^{tm1b(KOMP)Wtsi}/Tead1^{tm1b(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Tead1^{tm1b(KOMP)Wtsi}/Bay
• Cell Lines: EPD0207_2_C09

Data Sources

IMPC Data for Tead1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

abnormal embryo turning ( J:211773 )

♀

IMPC - BCM

abnormal embryo size ( J:211773 )

♀

IMPC - BCM

growth/size/body

abnormal embryo size ( J:211773 )

♀

IMPC - BCM

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - BCM

preweaning lethality, complete penetrance ( J:211773 )

IMPC - BCM

Genotype
MGI:5757796

ht2

• Allelic Composition: Tead1^{tm1b(KOMP)Wtsi}/Tead1⁺
• Genetic Background: C57BL/6N-Tead1^{tm1b(KOMP)Wtsi}/Bay
• Cell Lines: EPD0207_2_C09

Data Sources

IMPC Data for Tead1

adipose tissue

increased total body fat amount ( J:211773 )

♀

IMPC - BCM

craniofacial

abnormal tooth morphology ( J:211773 )

♀

IMPC - BCM

growth/size/body

abnormal tooth morphology ( J:211773 )

♀

IMPC - BCM

homeostasis/metabolism

impaired glucose tolerance ( J:211773 )

♀

IMPC - BCM

nervous system

decreased prepulse inhibition ( J:211773 )

♀

IMPC - BCM

skeleton

abnormal tooth morphology ( J:211773 )

♀

IMPC - BCM

vision/eye

decreased cornea thickness ( J:211773 )

IMPC - BCM

abnormal eye anterior chamber depth ( J:211773 )

♀

IMPC - BCM