Phenotypes associated with this allele

• Allele Symbol: Acvr2a^{tm1.1(KOMP)Vlcg}
• Allele Name: targeted mutation 1.1, Velocigene
• Allele ID: MGI:5548333
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Acvr2a^tm1.1(KOMP)Vlcg/Acvr2a^tm1.1(KOMP)Vlcg	C57BL/6N-Acvr2a^tm1.1(KOMP)Vlcg/Ucd	MGI:5639375
ht2	Acvr2a^tm1.1(KOMP)Vlcg/Acvr2a^+	C57BL/6N-Acvr2a^tm1.1(KOMP)Vlcg/Ucd	MGI:5759069

Genotype
MGI:5639375

hm1

• Allelic Composition: Acvr2a^{tm1.1(KOMP)Vlcg}/Acvr2a^{tm1.1(KOMP)Vlcg}
• Genetic Background: C57BL/6N-Acvr2a^{tm1.1(KOMP)Vlcg}/Ucd
• Cell Lines: 13054A-B9

Data Sources

IMPC Data for Acvr2a

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

craniofacial

abnormal craniofacial morphology ( J:211773 )

IMPC - TCP

embryo

abnormal embryo size ( J:211773 )

IMPC - TCP

growth/size/body

abnormal embryo size ( J:211773 )

IMPC - TCP

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - TCP

vision/eye

microphthalmia ( J:211773 )

IMPC - TCP

anophthalmia ( J:211773 )

IMPC - TCP

Genotype
MGI:5759069

ht2

• Allelic Composition: Acvr2a^{tm1.1(KOMP)Vlcg}/Acvr2a⁺
• Genetic Background: C57BL/6N-Acvr2a^{tm1.1(KOMP)Vlcg}/Ucd
• Cell Lines: 13054A-B9

Data Sources

IMPC Data for Acvr2a

behavior/neurological

abnormal behavior ( J:211773 )

♀

IMPC - TCP

increased thigmotaxis ( J:211773 )

♀

IMPC - TCP

hematopoietic system

decreased eosinophil cell number ( J:211773 )

♂

IMPC - TCP

decreased neutrophil cell number ( J:211773 )

♂

IMPC - TCP

immune system

decreased eosinophil cell number ( J:211773 )

♂

IMPC - TCP

decreased neutrophil cell number ( J:211773 )

♂

IMPC - TCP