Phenotypes associated with this allele

• Allele Symbol: Mbd6^{tm1.1(KOMP)Vlcg}
• Allele Name: targeted mutation 1.1, Velocigene
• Allele ID: MGI:5548367
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Mbd6^tm1.1(KOMP)Vlcg/Mbd6^tm1.1(KOMP)Vlcg	C57BL/6N-Mbd6^tm1.1(KOMP)Vlcg/Ucd	MGI:5631299
ht2	Mbd6^tm1.1(KOMP)Vlcg/Mbd6^+	C57BL/6N-Mbd6^tm1.1(KOMP)Vlcg/Ucd	MGI:5887441

Genotype
MGI:5631299

hm1

• Allelic Composition: Mbd6^{tm1.1(KOMP)Vlcg}/Mbd6^{tm1.1(KOMP)Vlcg}
• Genetic Background: C57BL/6N-Mbd6^{tm1.1(KOMP)Vlcg}/Ucd
• Cell Lines: 11562A-C8

Data Sources

IMPC Data for Mbd6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

hemorrhage ( J:211773 )

IMPC - UCD

craniofacial

abnormal craniofacial morphology ( J:211773 )

IMPC - UCD

cleft palate ( J:211773 )

IMPC - UCD

digestive/alimentary system

cleft palate ( J:211773 )

IMPC - UCD

embryo

spina bifida ( J:211773 )

IMPC - UCD

growth/size/body

cleft palate ( J:211773 )

IMPC - UCD

homeostasis/metabolism

edema ( J:211773 )

IMPC - UCD

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - UCD

nervous system

spina bifida ( J:211773 )

IMPC - UCD

Genotype
MGI:5887441

ht2

• Allelic Composition: Mbd6^{tm1.1(KOMP)Vlcg}/Mbd6⁺
• Genetic Background: C57BL/6N-Mbd6^{tm1.1(KOMP)Vlcg}/Ucd
• Cell Lines: 11562A-C8

Data Sources

IMPC Data for Mbd6

cardiovascular system

hemorrhage ( J:211773 )

IMPC - UCD

embryo

spina bifida ( J:211773 )

IMPC - UCD

growth/size/body

decreased body length ( J:211773 )

♀

IMPC - UCD

increased kidney weight ( J:211773 )

♂

IMPC - UCD

homeostasis/metabolism

increased fasting circulating glucose level ( J:211773 )

♀

IMPC - UCD

nervous system

spina bifida ( J:211773 )

IMPC - UCD

renal/urinary system

increased kidney weight ( J:211773 )

♂

IMPC - UCD