Phenotypes associated with this allele

• Allele Symbol: Plcb2^{tm1b(KOMP)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5548374
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Plcb2^tm1b(KOMP)Wtsi/Plcb2^tm1b(KOMP)Wtsi	C57BL/6N-Plcb2^tm1b(KOMP)Wtsi/MbpMmucd	MGI:6461536
hm2	Plcb2^tm1b(KOMP)Wtsi/Plcb2^tm1b(KOMP)Wtsi	C57BL/6N-Plcb2^tm1b(KOMP)Wtsi/Ucd	MGI:5631415

Genotype
MGI:6461536

hm1

• Allelic Composition: Plcb2^{tm1b(KOMP)Wtsi}/Plcb2^{tm1b(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Plcb2^{tm1b(KOMP)Wtsi}/MbpMmucd
• Cell Lines: EPD0182_1_F08

Data Sources

IMPC Data for Plcb2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

respiratory system

decreased pulmonary ventilation ( J:211773 )

♀

IMPC - TCP

Genotype
MGI:5631415

hm2

• Allelic Composition: Plcb2^{tm1b(KOMP)Wtsi}/Plcb2^{tm1b(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Plcb2^{tm1b(KOMP)Wtsi}/Ucd
• Cell Lines: EPD0182_1_F08

Data Sources

IMPC Data for Plcb2

behavior/neurological

decreased locomotor activity ( J:211773 )

IMPC - UCD

abnormal vocalization ( J:211773 )

♂

IMPC - UCD

growth/size/body

enlarged spleen ( J:211773 )

♀

IMPC - UCD

hematopoietic system

abnormal spleen morphology ( J:211773 )

♀

IMPC - UCD

enlarged spleen ( J:211773 )

♀

IMPC - UCD

immune system

abnormal spleen morphology ( J:211773 )

♀

IMPC - UCD

enlarged spleen ( J:211773 )

♀

IMPC - UCD

reproductive system

male infertility ( J:211773 )

♂

IMPC - UCD