Phenotypes associated with this allele

• Allele Symbol: Hdac1^{tm1b(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5548383
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Hdac1^tm1b(EUCOMM)Wtsi/Hdac1^tm1b(EUCOMM)Wtsi	C57BL/6N-Hdac1^tm1b(EUCOMM)Wtsi/Ieg	MGI:6262606
ht2	Hdac1^tm1b(EUCOMM)Wtsi/Hdac1^+	C57BL/6N-Hdac1^tm1b(EUCOMM)Wtsi/Ieg	MGI:6262605

Genotype
MGI:6262606

hm1

• Allelic Composition: Hdac1^{tm1b(EUCOMM)Wtsi}/Hdac1^{tm1b(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Hdac1^{tm1b(EUCOMM)Wtsi}/Ieg
• Cell Lines: EPD0028_5_G01

Data Sources

IMPC Data for Hdac1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - HMGU

Genotype
MGI:6262605

ht2

• Allelic Composition: Hdac1^{tm1b(EUCOMM)Wtsi}/Hdac1⁺
• Genetic Background: C57BL/6N-Hdac1^{tm1b(EUCOMM)Wtsi}/Ieg
• Cell Lines: EPD0028_5_G01

Data Sources

IMPC Data for Hdac1

behavior/neurological

decreased exploration in new environment ( J:211773 )

♂

IMPC - HMGU

cardiovascular system

cardiovascular system phenotype ( J:211773 )

IMPC - HMGU

decreased heart rate variability ( J:211773 )

IMPC - HMGU

hematopoietic system

decreased mean corpuscular hemoglobin ( J:211773 )

♀

IMPC - HMGU