All Phenotypes Nxn<tm1b(EUCOMM)Wtsi> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Nxn^{tm1b(EUCOMM)Wtsi}
targeted mutation 1b, Wellcome Trust Sanger Institute
MGI:5548389

Summary

20 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn^{tm1b(EUCOMM)Wtsi}	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/Bay	MGI:5757450
hm2	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn^{tm1b(EUCOMM)Wtsi}	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/Ccpcz	MGI:6480536
hm3	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn^{tm1b(EUCOMM)Wtsi}	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/H	MGI:5757453
hm4	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn^{tm1b(EUCOMM)Wtsi}	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/Ics	MGI:5757452
hm5	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn^{tm1b(EUCOMM)Wtsi}	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/Ieg	MGI:5757451
hm6	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn^{tm1b(EUCOMM)Wtsi}	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/J	MGI:5757448
hm7	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn^{tm1b(EUCOMM)Wtsi}	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/MbpMmucd	MGI:6394343
hm8	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn^{tm1b(EUCOMM)Wtsi}	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/Nju	MGI:5757454
hm9	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn^{tm1b(EUCOMM)Wtsi}	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/Rbrc	MGI:5757455
hm10	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn^{tm1b(EUCOMM)Wtsi}	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/Ucd	MGI:5757449
hm11	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn^{tm1b(EUCOMM)Wtsi}	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/Wtsi	MGI:5757456
ht12	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn⁺	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/Bay	MGI:5608339
ht13	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn⁺	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/Ccpcz	MGI:6461492
ht14	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn⁺	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/H	MGI:5757444
ht15	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn⁺	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/Ics	MGI:6263066
ht16	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn⁺	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/MbpMmucd	MGI:6325161
ht17	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn⁺	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/Nju	MGI:6263067
ht18	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn⁺	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/Rbrc	MGI:5757447
ht19	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn⁺	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/Ucd	MGI:5757446
ht20	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn⁺	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/Wtsi	MGI:5757443

Allelic Composition	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn^{tm1b(EUCOMM)Wtsi}
Genetic Background	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/Bay
Cell Lines	EPD0045_1_A11

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nxn^{tm1b(EUCOMM)Wtsi} mutation (2 available); any Nxn mutation (502 available)

Data Sources

IMPC Data for Nxn

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

unresponsive to tactile stimuli ( J:211773 )

IMPC - BCM

craniofacial

abnormal facial morphology ( J:211773 )

IMPC - BCM

cleft palate ( J:211773 )

IMPC - BCM

facial cleft ( J:211773 )

IMPC - BCM

abnormal head shape ( J:211773 )

IMPC - BCM

digestive/alimentary system

cleft palate ( J:211773 )

IMPC - BCM

embryo

abnormal embryo size ( J:211773 )

IMPC - BCM

growth/size/body

abnormal facial morphology ( J:211773 )

IMPC - BCM

cleft palate ( J:211773 )

IMPC - BCM

facial cleft ( J:211773 )

IMPC - BCM

abnormal head shape ( J:211773 )

IMPC - BCM

abnormal embryo size ( J:211773 )

IMPC - BCM

abnormal head size ( J:211773 )

IMPC - BCM

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - BCM

Allelic Composition	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn^{tm1b(EUCOMM)Wtsi}
Genetic Background	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/Ccpcz
Cell Lines	EPD0045_1_B11

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nxn^{tm1b(EUCOMM)Wtsi} mutation (2 available); any Nxn mutation (502 available)

Data Sources

IMPC Data for Nxn

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

no spontaneous movement ( J:211773 )

IMPC - CCP-IMG

craniofacial

abnormal facial morphology ( J:211773 )

IMPC - CCP-IMG

abnormal head shape ( J:211773 )

IMPC - CCP-IMG

growth/size/body

abnormal facial morphology ( J:211773 )

IMPC - CCP-IMG

abnormal head shape ( J:211773 )

IMPC - CCP-IMG

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - CCP-IMG

Allelic Composition	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn^{tm1b(EUCOMM)Wtsi}
Genetic Background	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/H
Cell Lines	EPD0045_1_B11

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nxn^{tm1b(EUCOMM)Wtsi} mutation (2 available); any Nxn mutation (502 available)

Data Sources

IMPC Data for Nxn

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - HAR

Allelic Composition	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn^{tm1b(EUCOMM)Wtsi}
Genetic Background	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/Ics
Cell Lines	EPD0045_1_B11

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nxn^{tm1b(EUCOMM)Wtsi} mutation (2 available); any Nxn mutation (502 available)

Data Sources

IMPC Data for Nxn

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - ICS

Allelic Composition	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn^{tm1b(EUCOMM)Wtsi}
Genetic Background	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/Ieg
Cell Lines	EPD0045_1_B11

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nxn^{tm1b(EUCOMM)Wtsi} mutation (2 available); any Nxn mutation (502 available)

Data Sources

IMPC Data for Nxn

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - HMGU

Allelic Composition	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn^{tm1b(EUCOMM)Wtsi}
Genetic Background	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/J
Cell Lines	EPD0045_1_A11

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nxn^{tm1b(EUCOMM)Wtsi} mutation (2 available); any Nxn mutation (502 available)

Data Sources

IMPC Data for Nxn

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

craniofacial

abnormal craniofacial morphology ( J:211773 )

IMPC - JAX

abnormal facial morphology ( J:211773 )

IMPC - JAX

cleft palate ( J:211773 )

IMPC - JAX

digestive/alimentary system

cleft palate ( J:211773 )

IMPC - JAX

embryo

abnormal embryo size ( J:211773 )

IMPC - JAX

growth/size/body

abnormal facial morphology ( J:211773 )

IMPC - JAX

cleft palate ( J:211773 )

IMPC - JAX

abnormal embryo size ( J:211773 )

IMPC - JAX

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - JAX

Allelic Composition	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn^{tm1b(EUCOMM)Wtsi}
Genetic Background	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/MbpMmucd
Cell Lines	EPD0045_1_A11

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nxn^{tm1b(EUCOMM)Wtsi} mutation (2 available); any Nxn mutation (502 available)

Data Sources

IMPC Data for Nxn

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - UCD

Allelic Composition	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn^{tm1b(EUCOMM)Wtsi}
Genetic Background	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/Nju
Cell Lines	EPD0045_1_A11

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nxn^{tm1b(EUCOMM)Wtsi} mutation (2 available); any Nxn mutation (502 available)

Data Sources

IMPC Data for Nxn

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - MARC

Allelic Composition	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn^{tm1b(EUCOMM)Wtsi}
Genetic Background	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/Rbrc
Cell Lines	EPD0045_1_A11

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nxn^{tm1b(EUCOMM)Wtsi} mutation (2 available); any Nxn mutation (502 available)

Data Sources

IMPC Data for Nxn

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - RBRC

Allelic Composition	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn^{tm1b(EUCOMM)Wtsi}
Genetic Background	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/Ucd
Cell Lines	EPD0045_1_A11

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nxn^{tm1b(EUCOMM)Wtsi} mutation (2 available); any Nxn mutation (502 available)

Data Sources

IMPC Data for Nxn

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

craniofacial

abnormal craniofacial morphology ( J:211773 )

IMPC - TCP

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - TCP

Allelic Composition	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn^{tm1b(EUCOMM)Wtsi}
Genetic Background	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/Wtsi
Cell Lines	EPD0045_1_B11

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nxn^{tm1b(EUCOMM)Wtsi} mutation (2 available); any Nxn mutation (502 available)

Data Sources

IMPC Data for Nxn

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cardiovascular system

absent stapedial artery ( J:239583 )

DMDD

dilated liver sinusoidal space ( J:239583 )

DMDD

abnormal vitelline vein topology ( J:239583 )

DMDD

double outlet right ventricle ( J:239583 )

DMDD

perimembraneous ventricular septal defect ( J:239583 )

DMDD

craniofacial

cleft palate ( J:239583 )

DMDD

digestive/alimentary system

cleft palate ( J:239583 )

DMDD

decreased intestine length ( J:239583 )

DMDD

embryo

abnormal vitelline vein topology ( J:239583 )

DMDD

abnormal Mullerian duct morphology ( J:239583 )

DMDD

growth/size/body

cleft palate ( J:239583 )

DMDD

hearing/vestibular/ear

absent stapedial artery ( J:239583 )

DMDD

liver/biliary system

dilated liver sinusoidal space ( J:239583 )

DMDD

herniated liver ( J:239583 )

DMDD

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - WTSI

Allelic Composition	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn⁺
Genetic Background	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/Bay
Cell Lines	EPD0045_1_A11

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nxn^{tm1b(EUCOMM)Wtsi} mutation (2 available); any Nxn mutation (502 available)

Data Sources

IMPC Data for Nxn

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

unresponsive to tactile stimuli ( J:211773 )

IMPC - BCM

Allelic Composition	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn⁺
Genetic Background	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/Ccpcz
Cell Lines	EPD0045_1_B11

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nxn^{tm1b(EUCOMM)Wtsi} mutation (2 available); any Nxn mutation (502 available)

Data Sources

IMPC Data for Nxn

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

endocrine/exocrine glands

abnormal mammary gland morphology ( J:211773 )

IMPC - CCP-IMG

hematopoietic system

increased effector memory CD8-positive, alpha-beta T cell number ( J:211773 )

IMPC - CCP-IMG

homeostasis/metabolism

increased circulating HDL cholesterol level ( J:211773 )

IMPC - CCP-IMG

increased circulating triglyceride level ( J:211773 )

IMPC - CCP-IMG

immune system

increased effector memory CD8-positive, alpha-beta T cell number ( J:211773 )

IMPC - CCP-IMG

integument

abnormal mammary gland morphology ( J:211773 )

IMPC - CCP-IMG

Allelic Composition	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn⁺
Genetic Background	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/H
Cell Lines	EPD0045_1_B11

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nxn^{tm1b(EUCOMM)Wtsi} mutation (2 available); any Nxn mutation (502 available)

Data Sources

IMPC Data for Nxn

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

craniofacial

abnormal snout morphology ( J:211773 )

IMPC - HAR

growth/size/body

abnormal snout morphology ( J:211773 )

IMPC - HAR

Allelic Composition	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn⁺
Genetic Background	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/Ics
Cell Lines	EPD0045_1_B11

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nxn^{tm1b(EUCOMM)Wtsi} mutation (2 available); any Nxn mutation (502 available)

Data Sources

IMPC Data for Nxn

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

decreased exploration in new environment ( J:211773 )

IMPC - ICS

abnormal freezing behavior ( J:211773 )

IMPC - ICS

abnormal locomotor behavior ( J:211773 )

IMPC - ICS

decreased locomotor activity ( J:211773 )

IMPC - ICS

homeostasis/metabolism

increased circulating alkaline phosphatase level ( J:211773 )

IMPC - ICS

limbs/digits/tail

abnormal digit morphology ( J:211773 )

IMPC - ICS

Allelic Composition	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn⁺
Genetic Background	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/MbpMmucd
Cell Lines	EPD0045_1_A11

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nxn^{tm1b(EUCOMM)Wtsi} mutation (2 available); any Nxn mutation (502 available)

Data Sources

IMPC Data for Nxn

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

short tibia ( J:211773 )

IMPC - UCD

skeleton

short tibia ( J:211773 )

IMPC - UCD

Allelic Composition	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn⁺
Genetic Background	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/Nju
Cell Lines	EPD0045_1_A11

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nxn^{tm1b(EUCOMM)Wtsi} mutation (2 available); any Nxn mutation (502 available)

Data Sources

IMPC Data for Nxn

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal optic disk morphology ( J:211773 )

IMPC - MARC

vision/eye

abnormal optic disk morphology ( J:211773 )

IMPC - MARC

Allelic Composition	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn⁺
Genetic Background	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/Rbrc
Cell Lines	EPD0045_1_A11

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nxn^{tm1b(EUCOMM)Wtsi} mutation (2 available); any Nxn mutation (502 available)

Data Sources

IMPC Data for Nxn

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

short tibia ( J:211773 )

IMPC - RBRC

skeleton

short tibia ( J:211773 )

IMPC - RBRC

Allelic Composition	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn⁺
Genetic Background	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/Ucd
Cell Lines	EPD0045_1_A11

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nxn^{tm1b(EUCOMM)Wtsi} mutation (2 available); any Nxn mutation (502 available)

Data Sources

IMPC Data for Nxn

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

endocrine/exocrine glands

small adrenal glands ( J:211773 )

IMPC - TCP

Allelic Composition	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn⁺
Genetic Background	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/Wtsi
Cell Lines	EPD0045_1_B11

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nxn^{tm1b(EUCOMM)Wtsi} mutation (2 available); any Nxn mutation (502 available)

Data Sources

IMPC Data for Nxn

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

craniofacial

abnormal cranium morphology ( J:211773 )

IMPC - WTSI

abnormal snout morphology ( J:211773 )

IMPC - WTSI

growth/size/body

abnormal snout morphology ( J:211773 )

IMPC - WTSI

skeleton

abnormal cranium morphology ( J:211773 )

IMPC - WTSI

vision/eye

abnormal eyelid morphology ( J:211773 )

IMPC - WTSI

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