Phenotypes associated with this allele

• Allele Symbol: Hipk2^{tm2b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 2b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5548422
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Hipk2^tm2b(EUCOMM)Hmgu/Hipk2^tm2b(EUCOMM)Hmgu	C57BL/6N-Hipk2^tm2b(EUCOMM)Hmgu/Cnrm	MGI:5757226
ht2	Hipk2^tm2b(EUCOMM)Hmgu/Hipk2^+	C57BL/6N-Hipk2^tm2b(EUCOMM)Hmgu/Cnrm	MGI:5757225

Genotype
MGI:5757226

hm1

• Allelic Composition: Hipk2^{tm2b(EUCOMM)Hmgu}/Hipk2^{tm2b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Hipk2^{tm2b(EUCOMM)Hmgu}/Cnrm
• Cell Lines: HEPD0547_7_F08

Data Sources

IMPC Data for Hipk2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

craniofacial

abnormal tooth morphology ( J:211773 )

IMPC - HAR

abnormal maxilla morphology ( J:211773 )

♂

IMPC - HAR

abnormal snout morphology ( J:211773 )

IMPC - HAR

growth/size/body

abnormal tooth morphology ( J:211773 )

IMPC - HAR

abnormal snout morphology ( J:211773 )

IMPC - HAR

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - HAR

skeleton

abnormal tooth morphology ( J:211773 )

IMPC - HAR

abnormal maxilla morphology ( J:211773 )

♂

IMPC - HAR

vision/eye

abnormal lens morphology ( J:211773 )

♂

IMPC - HAR

Genotype
MGI:5757225

ht2

• Allelic Composition: Hipk2^{tm2b(EUCOMM)Hmgu}/Hipk2⁺
• Genetic Background: C57BL/6N-Hipk2^{tm2b(EUCOMM)Hmgu}/Cnrm
• Cell Lines: HEPD0547_7_F08

Data Sources

IMPC Data for Hipk2

cardiovascular system

increased heart weight ( J:211773 )

♂

IMPC - HAR

growth/size/body

increased heart weight ( J:211773 )

♂

IMPC - HAR

increased kidney weight ( J:211773 )

♂

IMPC - HAR

renal/urinary system

increased kidney weight ( J:211773 )

♂

IMPC - HAR