All Phenotypes Slc40a1<tm1b(EUCOMM)Hmgu> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Slc40a1^{tm1b(EUCOMM)Hmgu}
targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
MGI:5548423

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Slc40a1^{tm1b(EUCOMM)Hmgu}/Slc40a1^{tm1b(EUCOMM)Hmgu}	C57BL/6N-Slc40a1^{tm1b(EUCOMM)Hmgu}/H	MGI:5757728
ht2	Slc40a1^{tm1b(EUCOMM)Hmgu}/Slc40a1⁺	C57BL/6N-Slc40a1^{tm1b(EUCOMM)Hmgu}/H	MGI:5757727

Allelic Composition	Slc40a1^{tm1b(EUCOMM)Hmgu}/Slc40a1^{tm1b(EUCOMM)Hmgu}
Genetic Background	C57BL/6N-Slc40a1^{tm1b(EUCOMM)Hmgu}/H
Cell Lines	HEPD0551_2_A07

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc40a1^{tm1b(EUCOMM)Hmgu} mutation (1 available); any Slc40a1 mutation (54 available)

Data Sources

IMPC Data for Slc40a1

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - HAR

preweaning lethality, complete penetrance ( J:211773 )

IMPC - HAR

Allelic Composition	Slc40a1^{tm1b(EUCOMM)Hmgu}/Slc40a1⁺
Genetic Background	C57BL/6N-Slc40a1^{tm1b(EUCOMM)Hmgu}/H
Cell Lines	HEPD0551_2_A07

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc40a1^{tm1b(EUCOMM)Hmgu} mutation (1 available); any Slc40a1 mutation (54 available)

Data Sources

IMPC Data for Slc40a1

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

adipose tissue

increased total body fat amount ( J:211773 )

IMPC - HAR

growth/size/body

decreased lean body mass ( J:211773 )

IMPC - HAR

homeostasis/metabolism

increased circulating triglyceride level ( J:211773 )

IMPC - HAR

skeleton

decreased bone mineral content ( J:211773 )

IMPC - HAR

decreased bone mineral density ( J:211773 )

IMPC - HAR

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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