Phenotypes associated with this allele

• Allele Symbol: Ggps1^{tm1b(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5548447
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ggps1^tm1b(EUCOMM)Wtsi/Ggps1^tm1b(EUCOMM)Wtsi	C57BL/6N-Ggps1^tm1b(EUCOMM)Wtsi/Ieg	MGI:5757172
ht2	Ggps1^tm1b(EUCOMM)Wtsi/Ggps1^+	C57BL/6N-Ggps1^tm1b(EUCOMM)Wtsi/Ieg	MGI:5757171

Genotype
MGI:5757172

hm1

• Allelic Composition: Ggps1^{tm1b(EUCOMM)Wtsi}/Ggps1^{tm1b(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Ggps1^{tm1b(EUCOMM)Wtsi}/Ieg
• Cell Lines: EPD0780_4_F04

Data Sources

IMPC Data for Ggps1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - HMGU

Genotype
MGI:5757171

ht2

• Allelic Composition: Ggps1^{tm1b(EUCOMM)Wtsi}/Ggps1⁺
• Genetic Background: C57BL/6N-Ggps1^{tm1b(EUCOMM)Wtsi}/Ieg
• Cell Lines: EPD0780_4_F04

Data Sources

IMPC Data for Ggps1

cardiovascular system

abnormal retina blood vessel morphology ( J:211773 )

♂

IMPC - HMGU

hematopoietic system

increased leukocyte cell number ( J:211773 )

♀

IMPC - HMGU

homeostasis/metabolism

increased circulating glucose level ( J:211773 )

♂

IMPC - HMGU

increased circulating cholesterol level ( J:211773 )

♂

IMPC - HMGU

increased circulating HDL cholesterol level ( J:211773 )

♂

IMPC - HMGU

impaired glucose tolerance ( J:211773 )

♂

IMPC - HMGU

immune system

increased leukocyte cell number ( J:211773 )

♀

IMPC - HMGU

integument

abnormal coat/ hair morphology ( J:211773 )

♀

IMPC - HMGU

vision/eye

abnormal retina blood vessel morphology ( J:211773 )

♂

IMPC - HMGU

abnormal lens morphology ( J:211773 )

♀

IMPC - HMGU

cataract ( J:211773 )

♀

IMPC - HMGU

abnormal vitreous body morphology ( J:211773 )

IMPC - HMGU