Phenotypes associated with this allele

• Allele Symbol: Gde1^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5548506
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Gde1^tm1b(EUCOMM)Hmgu/Gde1^tm1b(EUCOMM)Hmgu	C57BL/6N-Gde1^tm1b(EUCOMM)Hmgu/Ieg	MGI:6262513
ht2	Gde1^tm1b(EUCOMM)Hmgu/Gde1^+	C57BL/6N-Gde1^tm1b(EUCOMM)Hmgu/Ieg	MGI:6262512

Genotype
MGI:6262513

hm1

• Allelic Composition: Gde1^{tm1b(EUCOMM)Hmgu}/Gde1^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Gde1^{tm1b(EUCOMM)Hmgu}/Ieg
• Cell Lines: HEPD0680_5_F05

Data Sources

IMPC Data for Gde1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal behavior ( J:211773 )

IMPC - HMGU

decreased startle reflex ( J:211773 )

♀

IMPC - HMGU

abnormal gait ( J:211773 )

♀

IMPC - HMGU

decreased vertical activity ( J:211773 )

♀

IMPC - HMGU

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - HMGU

Genotype
MGI:6262512

ht2

• Allelic Composition: Gde1^{tm1b(EUCOMM)Hmgu}/Gde1⁺
• Genetic Background: C57BL/6N-Gde1^{tm1b(EUCOMM)Hmgu}/Ieg
• Cell Lines: HEPD0680_5_F05

Data Sources

IMPC Data for Gde1

behavior/neurological

abnormal behavior ( J:211773 )

IMPC - HMGU

increased vertical activity ( J:211773 )

♀

IMPC - HMGU

cardiovascular system

prolonged QRS complex duration ( J:211773 )

♂

IMPC - HMGU

hematopoietic system

decreased mean corpuscular volume ( J:211773 )

IMPC - HMGU

homeostasis/metabolism

increased circulating cholesterol level ( J:211773 )

♂

IMPC - HMGU

increased circulating alkaline phosphatase level ( J:211773 )

♀

IMPC - HMGU