Phenotypes associated with this allele

• Allele Symbol: Becn1^{tm1b(KOMP)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5548507
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Becn1^tm1b(KOMP)Wtsi/Becn1^tm1b(KOMP)Wtsi	C57BL/6N-Becn1^tm1b(KOMP)Wtsi/Ieg	MGI:6261973
ht2	Becn1^tm1b(KOMP)Wtsi/Becn1^+	C57BL/6N-Becn1^tm1b(KOMP)Wtsi/Ieg	MGI:6261972

Genotype
MGI:6261973

hm1

• Allelic Composition: Becn1^{tm1b(KOMP)Wtsi}/Becn1^{tm1b(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Becn1^{tm1b(KOMP)Wtsi}/Ieg
• Cell Lines: EPD0168_1_H11

Data Sources

IMPC Data for Becn1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - HMGU

Genotype
MGI:6261972

ht2

• Allelic Composition: Becn1^{tm1b(KOMP)Wtsi}/Becn1⁺
• Genetic Background: C57BL/6N-Becn1^{tm1b(KOMP)Wtsi}/Ieg
• Cell Lines: EPD0168_1_H11

Data Sources

IMPC Data for Becn1

adipose tissue

increased total body fat amount ( J:211773 )

♀

IMPC - HMGU

behavior/neurological

increased startle reflex ( J:211773 )

♂

IMPC - HMGU

growth/size/body

decreased lean body mass ( J:211773 )

♀

IMPC - HMGU

hematopoietic system

increased leukocyte cell number ( J:211773 )

IMPC - HMGU

homeostasis/metabolism

increased circulating bilirubin level ( J:211773 )

♀

IMPC - HMGU

decreased circulating HDL cholesterol level ( J:211773 )

♂

IMPC - HMGU

immune system

increased leukocyte cell number ( J:211773 )

IMPC - HMGU