Phenotypes associated with this allele

• Allele Symbol: Sarnp^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5548511
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Sarnp^tm1b(EUCOMM)Hmgu/Sarnp^tm1b(EUCOMM)Hmgu	C57BL/6N-Sarnp^tm1b(EUCOMM)Hmgu/Ieg	MGI:7267086
ht2	Sarnp^tm1b(EUCOMM)Hmgu/Sarnp^+	C57BL/6N-Sarnp^tm1b(EUCOMM)Hmgu/Ieg	MGI:5757675

Genotype
MGI:7267086

hm1

• Allelic Composition: Sarnp^{tm1b(EUCOMM)Hmgu}/Sarnp^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Sarnp^{tm1b(EUCOMM)Hmgu}/Ieg
• Cell Lines: HEPD0547_5_G11

Data Sources

IMPC Data for Sarnp

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - HMGU

Genotype
MGI:5757675

ht2

• Allelic Composition: Sarnp^{tm1b(EUCOMM)Hmgu}/Sarnp⁺
• Genetic Background: C57BL/6N-Sarnp^{tm1b(EUCOMM)Hmgu}/Ieg
• Cell Lines: HEPD0547_5_G11

Data Sources

IMPC Data for Sarnp

behavior/neurological

increased startle reflex ( J:211773 )

♂

IMPC - HMGU

hematopoietic system

increased mean corpuscular hemoglobin ( J:211773 )

IMPC - HMGU

vision/eye

abnormal lens morphology ( J:211773 )

♀

IMPC - HMGU

cataract ( J:211773 )

IMPC - HMGU

abnormal retina morphology ( J:211773 )

♀

IMPC - HMGU

decreased total retina thickness ( J:211773 )

♀

IMPC - HMGU

abnormal vitreous body morphology ( J:211773 )

♀

IMPC - HMGU