Phenotypes associated with this allele

• Allele Symbol: Tmem100^{tm1e.1(KOMP)Wtsi}
• Allele Name: targeted mutation 1e.1, Wellcome Trust Sanger Institute
• Allele ID: MGI:5548552
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tmem100^tm1e.1(KOMP)Wtsi/Tmem100^tm1e.1(KOMP)Wtsi	C57BL/6N-Tmem100^tm1e.1(KOMP)Wtsi/Tcp	MGI:5767828
ht2	Tmem100^tm1e.1(KOMP)Wtsi/Tmem100^+	C57BL/6N-Tmem100^tm1e.1(KOMP)Wtsi/Tcp	MGI:5767827

Genotype
MGI:5767828

hm1

• Allelic Composition: Tmem100^{tm1e.1(KOMP)Wtsi}/Tmem100^{tm1e.1(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Tmem100^{tm1e.1(KOMP)Wtsi}/Tcp
• Cell Lines: EPD0515_1_G05

Data Sources

IMPC Data for Tmem100

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal pericardium morphology ( J:211773 )

IMPC - TCP

embryo

abnormal embryo size ( J:211773 )

IMPC - TCP

pale yolk sac ( J:211773 )

IMPC - TCP

growth/size/body

abnormal embryo size ( J:211773 )

IMPC - TCP

homeostasis/metabolism

edema ( J:211773 )

IMPC - TCP

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - TCP

Genotype
MGI:5767827

ht2

• Allelic Composition: Tmem100^{tm1e.1(KOMP)Wtsi}/Tmem100⁺
• Genetic Background: C57BL/6N-Tmem100^{tm1e.1(KOMP)Wtsi}/Tcp
• Cell Lines: EPD0515_1_G05

Data Sources

IMPC Data for Tmem100

embryo

abnormal embryo size ( J:211773 )

IMPC - TCP

growth/size/body

abnormal embryo size ( J:211773 )

IMPC - TCP

hematopoietic system

increased leukocyte cell number ( J:211773 )

♀

IMPC - TCP

increased lymphocyte cell number ( J:211773 )

♀

IMPC - TCP

homeostasis/metabolism

decreased circulating calcium level ( J:211773 )

♂

IMPC - TCP

immune system

increased leukocyte cell number ( J:211773 )

♀

IMPC - TCP

increased lymphocyte cell number ( J:211773 )

♀

IMPC - TCP

respiratory system

abnormal lung morphology ( J:211773 )

♀

IMPC - TCP