Analysis Tools|
Allele Symbol Allele Name Allele ID |
Inf2tm1.1(KOMP)Vlcg targeted mutation 1.1, Velocigene MGI:5548597 |
||||||||||||
| Summary |
2 genotypes
|
|
|
Data Sources
|
| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
|
|
| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
|
• decrease in the number of maternal spiral arteries at E19.0
• fetal vascular density is increased in the labyrinth at E18.5
|
|
• the proportion of placental depth consisting of labyrinth but not junctional zone is significantly reduced
|
|
• decrease in the number of maternal spiral arteries at E19.0
• fetal vascular density is increased in the labyrinth at E18.5
|
 |
• increased blood pressure in pregnant females at day 17.5
• however at day 15.5 and postpartum day 2 blood pressure is similar to controls
|
|
• in the fetal umbilical artery end-diastolic velocity and pulsatility index are significantly elevated in fetuses at E18.5
• at E18.5, some umbilical vein waveforms appear pulsatile
|
|
• at E18.5; however, birth weight is similar to controls
• ratio of fetal to placental weight is reduced
|
|
• significantly growth restricted at E18.5
|
|
|
• gestation length is increased by 9.8 h compared to wild-type controls
• but pup weight, litter size and total litter weight are similar to wild-type controls
|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 11/12/2024 MGI 6.24 |
|
|
|
||
