Phenotypes associated with this allele

• Allele Symbol: Cep43^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5548654
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cep43^tm1b(EUCOMM)Hmgu/Cep43^tm1b(EUCOMM)Hmgu	C57BL/6N-Cep43^tm1b(EUCOMM)Hmgu/Ieg	MGI:5757121
ht2	Cep43^tm1b(EUCOMM)Hmgu/Cep43^+	C57BL/6N-Cep43^tm1b(EUCOMM)Hmgu/Ieg	MGI:5757120

Genotype
MGI:5757121

hm1

• Allelic Composition: Cep43^{tm1b(EUCOMM)Hmgu}/Cep43^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Cep43^{tm1b(EUCOMM)Hmgu}/Ieg
• Cell Lines: HEPD0550_7_C03

Data Sources

IMPC Data for Cep43

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - HMGU

Genotype
MGI:5757120

ht2

• Allelic Composition: Cep43^{tm1b(EUCOMM)Hmgu}/Cep43⁺
• Genetic Background: C57BL/6N-Cep43^{tm1b(EUCOMM)Hmgu}/Ieg
• Cell Lines: HEPD0550_7_C03

Data Sources

IMPC Data for Cep43

behavior/neurological

abnormal motor coordination/balance ( J:211773 )

IMPC - HMGU

cardiovascular system

abnormal retina vasculature morphology ( J:211773 )

IMPC - HMGU

abnormal retina blood vessel morphology ( J:211773 )

IMPC - HMGU

hematopoietic system

decreased mean corpuscular volume ( J:211773 )

IMPC - HMGU

homeostasis/metabolism

increased circulating alkaline phosphatase level ( J:211773 )

♀

IMPC - HMGU

vision/eye

abnormal retina vasculature morphology ( J:211773 )

IMPC - HMGU

abnormal retina blood vessel morphology ( J:211773 )

IMPC - HMGU

abnormal lens morphology ( J:211773 )

IMPC - HMGU

cataract ( J:211773 )

IMPC - HMGU