Phenotypes associated with this allele

• Allele Symbol: Nadsyn1^{tm1b(KOMP)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5548698
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Nadsyn1^tm1b(KOMP)Wtsi/Nadsyn1^tm1b(KOMP)Wtsi	C57BL/6N-Nadsyn1^tm1b(KOMP)Wtsi/MbpMmucd	MGI:6461465
hm2	Nadsyn1^tm1b(KOMP)Wtsi/Nadsyn1^tm1b(KOMP)Wtsi	C57BL/6N-Nadsyn1^tm1b(KOMP)Wtsi/Ucd	MGI:5797668

Genotype
MGI:6461465

hm1

• Allelic Composition: Nadsyn1^{tm1b(KOMP)Wtsi}/Nadsyn1^{tm1b(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Nadsyn1^{tm1b(KOMP)Wtsi}/MbpMmucd
• Cell Lines: EPD0119_4_A03

Data Sources

IMPC Data for Nadsyn1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

respiratory system

decreased pulmonary ventilation ( J:211773 )

♀

IMPC - TCP

increased pulmonary ventilation ( J:211773 )

♂

IMPC - TCP

Genotype
MGI:5797668

hm2

• Allelic Composition: Nadsyn1^{tm1b(KOMP)Wtsi}/Nadsyn1^{tm1b(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Nadsyn1^{tm1b(KOMP)Wtsi}/Ucd
• Cell Lines: EPD0119_4_A03

Data Sources

IMPC Data for Nadsyn1

behavior/neurological

decreased grip strength ( J:211773 )

♀

IMPC - UCD

cardiovascular system

decreased heart rate ( J:211773 )

♂

IMPC - UCD

prolonged RR interval ( J:211773 )

IMPC - UCD

prolonged ST segment ( J:211773 )

♀

IMPC - UCD

cornea vascularization ( J:211773 )

♀

IMPC - UCD

growth/size/body

enlarged spleen ( J:211773 )

♂

IMPC - UCD

hematopoietic system

enlarged spleen ( J:211773 )

♂

IMPC - UCD

immune system

enlarged spleen ( J:211773 )

♂

IMPC - UCD

reproductive system

female infertility ( J:211773 )

♀

IMPC - UCD

vision/eye

cornea vascularization ( J:211773 )

♀

IMPC - UCD

cornea opacity ( J:211773 )

IMPC - UCD