Analysis Tools|
Allele Symbol Allele Name Allele ID |
Nkg7tm1.1(KOMP)Vlcg targeted mutation 1.1, Velocigene MGI:5548721 |
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| Summary |
2 genotypes
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Data Sources
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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IMPC - UCD
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IMPC - UCD
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IMPC - UCD
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• reduced recruitment of MNCs into liver and limited expansion in spleen 14 days after infection with Leishmania donovani
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• reduced recruitment of CD4+ T cells into liver 14 days after infection with Leishmania donovani
• reduced levels of CD4+ CD11a+ CD49d+ T cells in liver 14 days after infection with L. donovani
• normal CD4+ T cell levels in spleen 14 days after infection with L. donovani
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• decreased T helper 1 cell number
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• reduced number in brain after infection with Plasmodium berghei ANKA
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• 14 days after infection with Leishmania donovani
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• 14 days after infection with Leishmania donovani
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• no development of severe neurological sequelae and longer survival till up to 13-14 days post-infection with Plasmodium berghei ANKA
• significantly reduced whole body and brain parasite burden
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• reduced capacity to control parasite growth in liver and spleen after infection with L donovani
• failure to clear liver infection 56 days after infection with Leishmania donovani
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• 14 days after infection with Leishmania donovani
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• 14 days after infection with Leishmania donovani
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• no development of severe neurological sequelae and longer survival till up to 13-14 days post-infection with Plasmodium berghei ANKA
• significantly reduced whole body and brain parasite burden
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• reduced capacity to control parasite growth in liver and spleen after infection with L donovani
• failure to clear liver infection 56 days after infection with Leishmania donovani
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| N |
• no significant hematological changes after infection with Leishmania donovani
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• reduced recruitment of MNCs into liver and limited expansion in spleen 14 days after infection with Leishmania donovani
|
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• reduced recruitment of CD4+ T cells into liver 14 days after infection with Leishmania donovani
• reduced levels of CD4+ CD11a+ CD49d+ T cells in liver 14 days after infection with L. donovani
• normal CD4+ T cell levels in spleen 14 days after infection with L. donovani
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• decreased T helper 1 cell number
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• reduced number in brain after infection with Plasmodium berghei ANKA
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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