Phenotypes associated with this allele

• Allele Symbol: Vps37d^{tm2b(EUCOMM)Wtsi}
• Allele Name: targeted mutation 2b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5548767
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Vps37d^tm2b(EUCOMM)Wtsi/Vps37d^tm2b(EUCOMM)Wtsi	C57BL/6N-Vps37d^tm2b(EUCOMM)Wtsi/Bay	MGI:5757879
ht2	Vps37d^tm2b(EUCOMM)Wtsi/Vps37d^+	C57BL/6N-Vps37d^tm2b(EUCOMM)Wtsi/Bay	MGI:5757878

Genotype
MGI:5757879

hm1

• Allelic Composition: Vps37d^{tm2b(EUCOMM)Wtsi}/Vps37d^{tm2b(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Vps37d^{tm2b(EUCOMM)Wtsi}/Bay
• Cell Lines: EPD0554_9_D02

Data Sources

IMPC Data for Vps37d

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

unresponsive to tactile stimuli ( J:211773 )

IMPC - BCM

growth/size/body

abnormal body wall morphology ( J:211773 )

IMPC - BCM

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - BCM

Genotype
MGI:5757878

ht2

• Allelic Composition: Vps37d^{tm2b(EUCOMM)Wtsi}/Vps37d⁺
• Genetic Background: C57BL/6N-Vps37d^{tm2b(EUCOMM)Wtsi}/Bay
• Cell Lines: EPD0554_9_D02

Data Sources

IMPC Data for Vps37d

behavior/neurological

unresponsive to tactile stimuli ( J:211773 )

IMPC - BCM

decreased locomotor activity ( J:211773 )

IMPC - BCM

nervous system

decreased prepulse inhibition ( J:211773 )

♂

IMPC - BCM

vision/eye

abnormal retina inner nuclear layer morphology ( J:211773 )

♀

IMPC - BCM

decreased total retina thickness ( J:211773 )

IMPC - BCM