Phenotypes associated with this allele

• Allele Symbol: Nae1^{tm1b(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5548785
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Nae1^tm1b(EUCOMM)Wtsi/Nae1^tm1b(EUCOMM)Wtsi	C57BL/6N-Nae1^tm1b(EUCOMM)Wtsi/Ics	MGI:5757398
ht2	Nae1^tm1b(EUCOMM)Wtsi/Nae1^+	C57BL/6N-Nae1^tm1b(EUCOMM)Wtsi/Ics	MGI:5757397

Genotype
MGI:5757398

hm1

• Allelic Composition: Nae1^{tm1b(EUCOMM)Wtsi}/Nae1^{tm1b(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Nae1^{tm1b(EUCOMM)Wtsi}/Ics
• Cell Lines: EPD0441_1_C08

Data Sources

IMPC Data for Nae1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - ICS

embryonic lethality prior to organogenesis ( J:211773 )

IMPC - ICS

preweaning lethality, complete penetrance ( J:211773 )

IMPC - ICS

Genotype
MGI:5757397

ht2

• Allelic Composition: Nae1^{tm1b(EUCOMM)Wtsi}/Nae1⁺
• Genetic Background: C57BL/6N-Nae1^{tm1b(EUCOMM)Wtsi}/Ics
• Cell Lines: EPD0441_1_C08

Data Sources

IMPC Data for Nae1

behavior/neurological

decreased exploration in new environment ( J:211773 )

♂

IMPC - ICS

hematopoietic system

decreased erythrocyte cell number ( J:211773 )

IMPC - ICS

increased mean corpuscular volume ( J:211773 )

♂

IMPC - ICS

homeostasis/metabolism

increased fasting circulating glucose level ( J:211773 )

♂

IMPC - ICS

increased circulating phosphate level ( J:211773 )

♂

IMPC - ICS